Professor Adams, along with Professor David Craik and colleagues from the University of Queensland's Institute for Molecular Bioscience, have described a surprising new way of inhibiting pain sensors using mini-proteins commonly found in cone snail venoms.
“For several years, it's been known that the remarkable properties of cone shell toxins (conotoxins) hold tremendous promise for chronic pain sufferers, and drugs that can combat or alleviate pain are a holy grail in drug discovery,” Professor Adams said.
The research paper of Professor David Adams invites scientists around the world to reconsider the conventional model for how conotoxins act on target cells such as sensory neurons, opening up what could be a paradigm shift in the development of conotoxin-based therapeutics and analgesics.
Source: Physorg
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