On 1st May'09, The University of Queensland, Australia has filed a patent in India for its alpha-conotoxin peptides
Application No: 8574/DELNP/2008
Title: CYCLISED ALPHA-CONOTOXIN PEPTIDES
Applicant: University of Queensland
Corresponding PCT: WO2007118270
Abstract: This invention relates to an oral or enteral pharmaceutical preparation comprising at least one synthetically cyclised alpha-conotoxinpeptide having an amide cyclised backbone such that the peptide has no free N- or C- terminus, said peptide having the ability toinhibit a nicotinic acetylcholine receptor and comprising four cysteine resdues bonded in pairs to form two disulfide bonds, whereinthe N-terminus of the corresponding linear/non-cyclised conotoxin peptide is linked to the C-terminus by a peptide linker, in a vehiclewhich is pharmaceutically suitable for oral or enteral administration.
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