A research publication in Toxicon from Renmin University of China suggest that "hydroxyproline residue is essential for the structure of conomarphin just like D-Phe13".
Dr. Huang et al, have published the article in the title, "Solution structure of Hyp10Pro variant of conomarphin, a cysteine-free and d-amino-acid containing conopeptide" that explains the unusual post-translational modification of conomarphin implies a unique selectivity of hydroxylation in toxin sequence.
Title: Solution structure of Hyp10Pro variant of conomarphin, a cysteine-free and d-amino-acid containing conopeptide.
Source: Pubmed
PMID: 19375441
Journal: Toxiocon
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